Urinary biomarkers of oxidative stress in atrial fibrillation

Lei Meng; Ricko Wong; Man Yin Tsui; Gary Tse; Guangping Li; Tong Liu; Gregory Y.H. Lip

doi:10.2174/1875318301808010024

Urinary biomarkers of oxidative stress in atrial fibrillation

Lei Meng, Ricko Wong, Man Yin Tsui, Gary Tse, Guangping Li, Tong Liu, Gregory Y.H. Lip

Research output: Contribution to journal › Review article › peer-review

Abstract

There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.

Original language	English
Pages (from-to)	24-33
Number of pages	10
Journal	Open Biomarkers Journal
Volume	8
Issue number	1
DOIs	https://doi.org/10.2174/1875318301808010024
Publication status	Published - 2018
Externally published	Yes

Keywords

8-OHdG
Antioxidant
Atrial fibrillation
CRP
IL-6
Inflammation
Isoprostanes
NADPH oxidase
Oxidative stress
Urinary biomarkers

Access to Document

10.2174/1875318301808010024

Cite this

@article{397c7b13033c4cc6aa9759d06db7ca85,

title = "Urinary biomarkers of oxidative stress in atrial fibrillation",

abstract = "There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.",

keywords = "8-OHdG, Antioxidant, Atrial fibrillation, CRP, IL-6, Inflammation, Isoprostanes, NADPH oxidase, Oxidative stress, Urinary biomarkers",

author = "Lei Meng and Ricko Wong and Tsui, {Man Yin} and Gary Tse and Guangping Li and Tong Liu and Lip, {Gregory Y.H.}",

note = "Publisher Copyright: {\textcopyright} 2018 Meng et al.",

year = "2018",

doi = "10.2174/1875318301808010024",

language = "English",

volume = "8",

pages = "24--33",

number = "1",

}

TY - JOUR

T1 - Urinary biomarkers of oxidative stress in atrial fibrillation

AU - Meng, Lei

AU - Wong, Ricko

AU - Tsui, Man Yin

AU - Tse, Gary

AU - Li, Guangping

AU - Liu, Tong

AU - Lip, Gregory Y.H.

PY - 2018

Y1 - 2018

N2 - There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.

AB - There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.

KW - 8-OHdG

KW - Antioxidant

KW - Atrial fibrillation

KW - CRP

KW - IL-6

KW - Inflammation

KW - Isoprostanes

KW - NADPH oxidase

KW - Oxidative stress

KW - Urinary biomarkers

UR - http://www.scopus.com/inward/record.url?scp=85061738359&partnerID=8YFLogxK

U2 - 10.2174/1875318301808010024

DO - 10.2174/1875318301808010024

M3 - Review article

AN - SCOPUS:85061738359

VL - 8

SP - 24

EP - 33

JO - Open Biomarkers Journal

JF - Open Biomarkers Journal

IS - 1

ER -

Urinary biomarkers of oxidative stress in atrial fibrillation

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this