Toxicology and evaluation of microcystins

Paul K.S. Lam; Mengsu Yang; Michael H.W. Lam

doi:10.1097/00007691-200002000-00015

Toxicology and evaluation of microcystins

Paul K.S. Lam
, Mengsu Yang
, Michael H.W. Lam

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

This paper reviews the toxicity and tumor-promoting properties of microcystins. Methods for screening and/or identification of microcystins in environmental samples are discussed and compared. Specific emphasis is placed on newly developed extraction/detection methods, e.g., solid phase microextraction (SPME) technique, and capillary electrophoresis coupled with laser-induced fluorescence detection. The results of a kinetic analysis of the effects of microcystins on phosphorylase-a binding to phosphatase-2A using a surface plasmon resonance biosensor are also presented.

Original language	English
Pages (from-to)	69-72
Number of pages	4
Journal	Therapeutic Drug Monitoring
Volume	22
Issue number	1
DOIs	https://doi.org/10.1097/00007691-200002000-00015
Publication status	Published - 2000
Externally published	Yes

Keywords

Biosensor technology
Microcystins
Solid phase microextraction

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10.1097/00007691-200002000-00015

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title = "Toxicology and evaluation of microcystins",

abstract = "This paper reviews the toxicity and tumor-promoting properties of microcystins. Methods for screening and/or identification of microcystins in environmental samples are discussed and compared. Specific emphasis is placed on newly developed extraction/detection methods, e.g., solid phase microextraction (SPME) technique, and capillary electrophoresis coupled with laser-induced fluorescence detection. The results of a kinetic analysis of the effects of microcystins on phosphorylase-a binding to phosphatase-2A using a surface plasmon resonance biosensor are also presented.",

keywords = "Biosensor technology, Microcystins, Solid phase microextraction",

author = "Lam, \{Paul K.S.\} and Mengsu Yang and Lam, \{Michael H.W.\}",

year = "2000",

doi = "10.1097/00007691-200002000-00015",

language = "English",

volume = "22",

pages = "69--72",

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T1 - Toxicology and evaluation of microcystins

AU - Lam, Paul K.S.

AU - Yang, Mengsu

AU - Lam, Michael H.W.

PY - 2000

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N2 - This paper reviews the toxicity and tumor-promoting properties of microcystins. Methods for screening and/or identification of microcystins in environmental samples are discussed and compared. Specific emphasis is placed on newly developed extraction/detection methods, e.g., solid phase microextraction (SPME) technique, and capillary electrophoresis coupled with laser-induced fluorescence detection. The results of a kinetic analysis of the effects of microcystins on phosphorylase-a binding to phosphatase-2A using a surface plasmon resonance biosensor are also presented.

AB - This paper reviews the toxicity and tumor-promoting properties of microcystins. Methods for screening and/or identification of microcystins in environmental samples are discussed and compared. Specific emphasis is placed on newly developed extraction/detection methods, e.g., solid phase microextraction (SPME) technique, and capillary electrophoresis coupled with laser-induced fluorescence detection. The results of a kinetic analysis of the effects of microcystins on phosphorylase-a binding to phosphatase-2A using a surface plasmon resonance biosensor are also presented.

KW - Biosensor technology

KW - Microcystins

KW - Solid phase microextraction

UR - https://www.scopus.com/pages/publications/0033961952

U2 - 10.1097/00007691-200002000-00015

DO - 10.1097/00007691-200002000-00015

M3 - Article

C2 - 10688263

AN - SCOPUS:0033961952

SN - 0163-4356

VL - 22

SP - 69

EP - 72

JO - Therapeutic Drug Monitoring

JF - Therapeutic Drug Monitoring

IS - 1

ER -

Toxicology and evaluation of microcystins

Abstract

Keywords

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