TY - JOUR
T1 - The role of myocardial fibrosis in determining the success rate of ablation for the treatment of atrial fibrillation
AU - Selvendran, Subothini
AU - Aggarwal, Nikhil
AU - Li, Justin
AU - Tse, Gary
AU - Vassiliou, Vassilios S.
N1 - Publisher Copyright:
© 2017 Edizioni Minerva Medica.
PY - 2017/8
Y1 - 2017/8
N2 - Atrial fibrillation is the most common sustained cardiac arrhythmia and with an aging population its prevalence will increase. In addition to appropriate anticoagulation to reduce the thromboembolic risk, there has been an increasing need for a personalized approach in identifying which patients are likely to benefit more from atrial fibrillation ablation procedures. This review will discuss the role of myocardial fibrosis in patients with atrial fibrillation, its mechanistic role, association with biomarkers and how this could potentially be of use in the development of a risk score identifying the success of maintaining sinus rhythm following an electrophysiological ablation.
AB - Atrial fibrillation is the most common sustained cardiac arrhythmia and with an aging population its prevalence will increase. In addition to appropriate anticoagulation to reduce the thromboembolic risk, there has been an increasing need for a personalized approach in identifying which patients are likely to benefit more from atrial fibrillation ablation procedures. This review will discuss the role of myocardial fibrosis in patients with atrial fibrillation, its mechanistic role, association with biomarkers and how this could potentially be of use in the development of a risk score identifying the success of maintaining sinus rhythm following an electrophysiological ablation.
KW - Ablation techniques
KW - Atrial fibrillation
KW - Endomyocardial fibrosis
UR - http://www.scopus.com/inward/record.url?scp=85021189138&partnerID=8YFLogxK
U2 - 10.23736/S0026-4725.17.04371-7
DO - 10.23736/S0026-4725.17.04371-7
M3 - Review article
C2 - 28274110
AN - SCOPUS:85021189138
SN - 0026-4725
VL - 65
SP - 420
EP - 426
JO - Minerva Cardioangiologica
JF - Minerva Cardioangiologica
IS - 4
ER -