The role of myocardial fibrosis in determining the success rate of ablation for the treatment of atrial fibrillation

Subothini Selvendran, Nikhil Aggarwal, Justin Li, Gary Tse, Vassilios S. Vassiliou

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)

Abstract

Atrial fibrillation is the most common sustained cardiac arrhythmia and with an aging population its prevalence will increase. In addition to appropriate anticoagulation to reduce the thromboembolic risk, there has been an increasing need for a personalized approach in identifying which patients are likely to benefit more from atrial fibrillation ablation procedures. This review will discuss the role of myocardial fibrosis in patients with atrial fibrillation, its mechanistic role, association with biomarkers and how this could potentially be of use in the development of a risk score identifying the success of maintaining sinus rhythm following an electrophysiological ablation.

Original languageEnglish
Pages (from-to)420-426
Number of pages7
JournalMinerva Cardioangiologica
Volume65
Issue number4
DOIs
Publication statusPublished - Aug 2017
Externally publishedYes

Keywords

  • Ablation techniques
  • Atrial fibrillation
  • Endomyocardial fibrosis

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