Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands

Quan Tang; Wen Xiu Ni; Chi Fai Leung; Wai Lun Man; Kenneth King Kwan Lau; Yimin Liang; Yun Wah Lam; Wai Yeung Wong; Shie Ming Peng; Gui Jian Liu; Tai Chu Lau

doi:10.1039/c3cc42250j

Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands

Quan Tang
, Wen Xiu Ni
, Chi Fai Leung
, Wai Lun Man
, Kenneth King Kwan Lau
, Yimin Liang
, Yun Wah Lam
, Wai Yeung Wong
, Shie Ming Peng
, Gui Jian Liu
, Tai Chu Lau

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that Os^VI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

Original language	English
Pages (from-to)	9980-9982
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	85
DOIs	https://doi.org/10.1039/c3cc42250j
Publication status	Published - Oct 2013
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/c3cc42250j

Cite this

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title = "Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands",

abstract = "A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.",

author = "Quan Tang and Ni, \{Wen Xiu\} and Leung, \{Chi Fai\} and Man, \{Wai Lun\} and Lau, \{Kenneth King Kwan\} and Yimin Liang and Lam, \{Yun Wah\} and Wong, \{Wai Yeung\} and Peng, \{Shie Ming\} and Liu, \{Gui Jian\} and Lau, \{Tai Chu\}",

year = "2013",

month = oct,

doi = "10.1039/c3cc42250j",

language = "English",

volume = "49",

pages = "9980--9982",

number = "85",

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T1 - Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands

AU - Tang, Quan

AU - Ni, Wen Xiu

AU - Leung, Chi Fai

AU - Man, Wai Lun

AU - Lau, Kenneth King Kwan

AU - Liang, Yimin

AU - Lam, Yun Wah

AU - Wong, Wai Yeung

AU - Peng, Shie Ming

AU - Liu, Gui Jian

AU - Lau, Tai Chu

PY - 2013/10

Y1 - 2013/10

N2 - A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

AB - A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

UR - https://www.scopus.com/pages/publications/84885155074

U2 - 10.1039/c3cc42250j

DO - 10.1039/c3cc42250j

M3 - Article

C2 - 24042270

AN - SCOPUS:84885155074

SN - 1359-7345

VL - 49

SP - 9980

EP - 9982

JO - Chemical Communications

JF - Chemical Communications

IS - 85

ER -

Synthesis and antitumor activity of a series of osmium(IV) nitrido complexes bearing quinolinolato ligands

Abstract

UN SDGs

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