Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy

Wenfeng Shangguan; Gang Xu; Xin Wang; Nan Zhang; Xingpeng Liu; Guangping Li; Gary Tse; Tong Liu

doi:10.3390/jcm11123549

Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy

Wenfeng Shangguan, Gang Xu, Xin Wang, Nan Zhang, Xingpeng Liu, Guangping Li, Gary Tse, Tong Liu

Research output: Contribution to journal › Review article › peer-review

5 Citations (Scopus)

Abstract

Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.

Original language	English
Article number	3549
Journal	Journal of Clinical Medicine
Volume	11
Issue number	12
DOIs	https://doi.org/10.3390/jcm11123549
Publication status	Published - 1 Jun 2022
Externally published	Yes

Keywords

refractory ventricular tachycardia
stereotactic body radiotherapy
treatment

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10.3390/jcm11123549

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title = "Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy",

abstract = "Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.",

keywords = "refractory ventricular tachycardia, stereotactic body radiotherapy, treatment",

author = "Wenfeng Shangguan and Gang Xu and Xin Wang and Nan Zhang and Xingpeng Liu and Guangping Li and Gary Tse and Tong Liu",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2022",

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doi = "10.3390/jcm11123549",

language = "English",

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TY - JOUR

T1 - Stereotactic Radiotherapy

T2 - An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy

AU - Shangguan, Wenfeng

AU - Xu, Gang

AU - Wang, Xin

AU - Zhang, Nan

AU - Liu, Xingpeng

AU - Li, Guangping

AU - Tse, Gary

AU - Liu, Tong

PY - 2022/6/1

Y1 - 2022/6/1

N2 - Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.

AB - Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.

KW - refractory ventricular tachycardia

KW - stereotactic body radiotherapy

KW - treatment

UR - http://www.scopus.com/inward/record.url?scp=85132137796&partnerID=8YFLogxK

U2 - 10.3390/jcm11123549

DO - 10.3390/jcm11123549

M3 - Review article

AN - SCOPUS:85132137796

VL - 11

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

IS - 12

M1 - 3549

ER -

Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy

Abstract

Keywords

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