Risk factors of dementia in type 2 diabetes mellitus: The Hong Kong diabetes study

Yau Lam Alex Chau, Ji Won Yoo, Jiandong Zhou, Cosmos LiutaoGuo, Wing Tak Wong, Carlin Chang, Tong Liu, Kamalan Jeevaratnam, Qingpeng Zhang, Gary Tse, Sharen Lee

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

This population-based cohort study investigated the risk factors of incident dementia and vascular dementia in type 2 diabetic patients (≥45 years old) attending the Hong Kong Hospital Authority between 1st January and 31st December 2009.Of the 273,876 patients included,9994 showed incident dementia (median follow-up: 4245 days). Multivariable Cox regression identified older age (HR: 1.09 [95% CI: 1.08–1.10]) and antiplatelet use (HR: 1.36 [1.14–1.62]) as risk factors for incident dementia, and older age (HR: 1.07 [1.06–1.08]), ischemic stroke (HR: 1.47 [1.09–1.98]), fasting blood glucose (HR: 1.10 [1.01–1.20]), antiplatelets (HR: 1.92 [1.51–2.44]), and calcium channel blocker (HR: 1.28 [1.04–1.57]) use as risk factors of incident vascular dementia.

Original languageEnglish
Article number100155
JournalAging and Health Research
Volume3
Issue number3
DOIs
Publication statusPublished - Sept 2023

Keywords

  • Dementia
  • Risk factors
  • Type 2 diabetes
  • Vascular

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