Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y)

Ariel K.M. Chow; Nathan S.M. Cheng; Colin S.C. Lam; Lui Ng; Sunny K.M. Wong; Timothy M.H. Wan; Johnny H.W. Man; Alvin H.K. Cheung; Thomas C.C. Yau; Jensen T.C. Poon; Wai Lun Law; Roberta W.C. Pang

doi:10.1186/s12943-025-02535-z

Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y)

Ariel K.M. Chow
, Nathan S.M. Cheng
, Colin S.C. Lam
, Lui Ng
, Sunny K.M. Wong
, Timothy M.H. Wan
, Johnny H.W. Man
, Alvin H.K. Cheung
, Thomas C.C. Yau
, Jensen T.C. Poon
, Wai Lun Law
, Roberta W.C. Pang

Research output: Contribution to journal › Comment/debate

Abstract

The Editor-in-Chief has retracted this article. A number of image integrity concerns were raised after publication. Specifically: two panels in Fig. 4B, HT29 Saline and Raf265, appear to overlap with two panels of Fig. 5B Anti-CD31 of a previously published paper [1]. two panels in Fig. 4B, HTC116 Saline and Raf265, appear to overlap with two panels of Fig. 5A Anti-CD31 in the same previously published paper [1]. The authors have not responded to correspondence about these concerns. The Editor-in-Chief has lost confidence in the data and conclusions of this article. Author Ariel Chow disagrees with this retraction. All other authors have not responded to correspondence regarding this retraction.

Original language	English
Article number	302
Journal	Molecular Cancer
Volume	24
Issue number	1
DOIs	https://doi.org/10.1186/s12943-025-02535-z
Publication status	Published - Dec 2025
Externally published	Yes

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Chow, A. K. M., Cheng, N. S. M., Lam, C. S. C., Ng, L., Wong, S. K. M., Wan, T. M. H., Man, J. H. W., Cheung, A. H. K., Yau, T. C. C., Poon, J. T. C., Law, W. L., & Pang, R. W. C. (2025). Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y). Molecular Cancer, 24(1), Article 302. https://doi.org/10.1186/s12943-025-02535-z

@article{903048b728f441af91f20a60e5471457,

title = "Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y)",

abstract = "The Editor-in-Chief has retracted this article. A number of image integrity concerns were raised after publication. Specifically: two panels in Fig. 4B, HT29 Saline and Raf265, appear to overlap with two panels of Fig. 5B Anti-CD31 of a previously published paper [1]. two panels in Fig. 4B, HTC116 Saline and Raf265, appear to overlap with two panels of Fig. 5A Anti-CD31 in the same previously published paper [1]. The authors have not responded to correspondence about these concerns. The Editor-in-Chief has lost confidence in the data and conclusions of this article. Author Ariel Chow disagrees with this retraction. All other authors have not responded to correspondence regarding this retraction.",

author = "Chow, \{Ariel K.M.\} and Cheng, \{Nathan S.M.\} and Lam, \{Colin S.C.\} and Lui Ng and Wong, \{Sunny K.M.\} and Wan, \{Timothy M.H.\} and Man, \{Johnny H.W.\} and Cheung, \{Alvin H.K.\} and Yau, \{Thomas C.C.\} and Poon, \{Jensen T.C.\} and Law, \{Wai Lun\} and Pang, \{Roberta W.C.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2025.",

year = "2025",

month = dec,

doi = "10.1186/s12943-025-02535-z",

language = "English",

volume = "24",

number = "1",

}

Chow, AKM, Cheng, NSM, Lam, CSC, Ng, L, Wong, SKM, Wan, TMH, Man, JHW, Cheung, AHK, Yau, TCC, Poon, JTC, Law, WL & Pang, RWC 2025, 'Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y)', Molecular Cancer, vol. 24, no. 1, 302. https://doi.org/10.1186/s12943-025-02535-z

Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y). / Chow, Ariel K.M.; Cheng, Nathan S.M.; Lam, Colin S.C. et al.
In: Molecular Cancer, Vol. 24, No. 1, 302, 12.2025.

Research output: Contribution to journal › Comment/debate

TY - JOUR

T1 - Retraction note

T2 - Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y)

AU - Chow, Ariel K.M.

AU - Cheng, Nathan S.M.

AU - Lam, Colin S.C.

AU - Ng, Lui

AU - Wong, Sunny K.M.

AU - Wan, Timothy M.H.

AU - Man, Johnny H.W.

AU - Cheung, Alvin H.K.

AU - Yau, Thomas C.C.

AU - Poon, Jensen T.C.

AU - Law, Wai Lun

AU - Pang, Roberta W.C.

PY - 2025/12

Y1 - 2025/12

N2 - The Editor-in-Chief has retracted this article. A number of image integrity concerns were raised after publication. Specifically: two panels in Fig. 4B, HT29 Saline and Raf265, appear to overlap with two panels of Fig. 5B Anti-CD31 of a previously published paper [1]. two panels in Fig. 4B, HTC116 Saline and Raf265, appear to overlap with two panels of Fig. 5A Anti-CD31 in the same previously published paper [1]. The authors have not responded to correspondence about these concerns. The Editor-in-Chief has lost confidence in the data and conclusions of this article. Author Ariel Chow disagrees with this retraction. All other authors have not responded to correspondence regarding this retraction.

AB - The Editor-in-Chief has retracted this article. A number of image integrity concerns were raised after publication. Specifically: two panels in Fig. 4B, HT29 Saline and Raf265, appear to overlap with two panels of Fig. 5B Anti-CD31 of a previously published paper [1]. two panels in Fig. 4B, HTC116 Saline and Raf265, appear to overlap with two panels of Fig. 5A Anti-CD31 in the same previously published paper [1]. The authors have not responded to correspondence about these concerns. The Editor-in-Chief has lost confidence in the data and conclusions of this article. Author Ariel Chow disagrees with this retraction. All other authors have not responded to correspondence regarding this retraction.

UR - https://www.scopus.com/pages/publications/105023334397

U2 - 10.1186/s12943-025-02535-z

DO - 10.1186/s12943-025-02535-z

M3 - Comment/debate

C2 - 41316258

AN - SCOPUS:105023334397

VL - 24

JO - Molecular Cancer

JF - Molecular Cancer

IS - 1

M1 - 302

ER -

Retraction note: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma (Molecular Cancer, (2015), 14, 1, (80), 10.1186/s12943-015-0352-y)

Abstract

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