Physiological responses of the alga Cyclotella caspia to bisphenol A exposure

Rui Li, Yu Liu, Guizhu Chen, Nora F.Y. Tam, Paul K.S. Shin, Sin Gin Cheung, Tiangang Luan

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The endocrine-disrupting chemical bisphenol A (BPA) has attracted attention because of its estrogenic activity and its extensive environmental distribution. The objective of this study was to investigate the physiological response of the alga Cyclotella caspia, a dominant species isolated from Futian Nature Mangrove Reserve, Shenzhen, China, to BPA at different concentrations (4, 6, 8, 10 and 12 mg l-1). We studied the effects of BPA on biomass, growth rate, chlorophyll (chl) a content, cellular morphology, and superoxide dismutase (SOD) activity of C. caspia. The effective concentration of BPA that inhibited algal growth by 50% at 96 h was 7.96±0.23 mg l-1. Algal biomass, growth rate and chl a content decreased with increasing BPA concentration. BPA concentrations greater than 6 mg l-1 strongly inhibited cell division, significantly increased cell volume, and caused cellular inclusions to appear. SOD activity increased with the BPA concentration, but decreased with prolonged exposure time, showing a dynamic process from induction to inhibition. Our results provide baseline information for the development of marine ecotoxicology and physiology theories concerning BPA.

Original languageEnglish
Pages (from-to)360-369
Number of pages10
JournalBotanica Marina
Volume51
Issue number5
DOIs
Publication statusPublished - 1 Oct 2008
Externally publishedYes

Keywords

  • Alga
  • Bisphenol A
  • Cyclotella caspia
  • Physiological response

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