TY - JOUR
T1 - Physiological responses of the alga Cyclotella caspia to bisphenol A exposure
AU - Li, Rui
AU - Liu, Yu
AU - Chen, Guizhu
AU - Tam, Nora F.Y.
AU - Shin, Paul K.S.
AU - Cheung, Sin Gin
AU - Luan, Tiangang
N1 - Funding Information:
This study was supported by grants from the National Natural Science Foundation of China (No. 40576057) and the Guangdong Provincial Natural Science Foundation of China (No. 031549). The authors gratefully acknowledge Y.S. Wong, Lilian L.P. Kwan Vrijmoed, W. Luo and N.N. Lu.
PY - 2008/10/1
Y1 - 2008/10/1
N2 - The endocrine-disrupting chemical bisphenol A (BPA) has attracted attention because of its estrogenic activity and its extensive environmental distribution. The objective of this study was to investigate the physiological response of the alga Cyclotella caspia, a dominant species isolated from Futian Nature Mangrove Reserve, Shenzhen, China, to BPA at different concentrations (4, 6, 8, 10 and 12 mg l-1). We studied the effects of BPA on biomass, growth rate, chlorophyll (chl) a content, cellular morphology, and superoxide dismutase (SOD) activity of C. caspia. The effective concentration of BPA that inhibited algal growth by 50% at 96 h was 7.96±0.23 mg l-1. Algal biomass, growth rate and chl a content decreased with increasing BPA concentration. BPA concentrations greater than 6 mg l-1 strongly inhibited cell division, significantly increased cell volume, and caused cellular inclusions to appear. SOD activity increased with the BPA concentration, but decreased with prolonged exposure time, showing a dynamic process from induction to inhibition. Our results provide baseline information for the development of marine ecotoxicology and physiology theories concerning BPA.
AB - The endocrine-disrupting chemical bisphenol A (BPA) has attracted attention because of its estrogenic activity and its extensive environmental distribution. The objective of this study was to investigate the physiological response of the alga Cyclotella caspia, a dominant species isolated from Futian Nature Mangrove Reserve, Shenzhen, China, to BPA at different concentrations (4, 6, 8, 10 and 12 mg l-1). We studied the effects of BPA on biomass, growth rate, chlorophyll (chl) a content, cellular morphology, and superoxide dismutase (SOD) activity of C. caspia. The effective concentration of BPA that inhibited algal growth by 50% at 96 h was 7.96±0.23 mg l-1. Algal biomass, growth rate and chl a content decreased with increasing BPA concentration. BPA concentrations greater than 6 mg l-1 strongly inhibited cell division, significantly increased cell volume, and caused cellular inclusions to appear. SOD activity increased with the BPA concentration, but decreased with prolonged exposure time, showing a dynamic process from induction to inhibition. Our results provide baseline information for the development of marine ecotoxicology and physiology theories concerning BPA.
KW - Alga
KW - Bisphenol A
KW - Cyclotella caspia
KW - Physiological response
UR - http://www.scopus.com/inward/record.url?scp=53649106025&partnerID=8YFLogxK
U2 - 10.1515/BOT.2008.050
DO - 10.1515/BOT.2008.050
M3 - Article
AN - SCOPUS:53649106025
SN - 0006-8055
VL - 51
SP - 360
EP - 369
JO - Botanica Marina
JF - Botanica Marina
IS - 5
ER -
