TY - JOUR
T1 - Photofunctional cyclometallated iridium(iii) polypyridine methylsulfone complexes as sulfhydryl-specific reagents for bioconjugation, bioimaging and photocytotoxic applications
AU - Huang, Lili
AU - Leung, Peter Kam Keung
AU - Lee, Lawrence Cho Cheung
AU - Xu, Guang Xi
AU - Lam, Yun Wah
AU - Lo, Kenneth Kam Wing
N1 - Publisher Copyright:
© 2022 The Royal Society of Chemistry.
PY - 2022/8/8
Y1 - 2022/8/8
N2 - We report herein near-infrared (NIR)-emitting cyclometallated iridium(iii) complexes bearing a heteroaromatic methylsulfone moiety as sulfhydryl-specific reagents; one of the complexes was conjugated to cysteine and cysteine-containing peptides and proteins for bioimaging and photocytotoxic applications.
AB - We report herein near-infrared (NIR)-emitting cyclometallated iridium(iii) complexes bearing a heteroaromatic methylsulfone moiety as sulfhydryl-specific reagents; one of the complexes was conjugated to cysteine and cysteine-containing peptides and proteins for bioimaging and photocytotoxic applications.
UR - http://www.scopus.com/inward/record.url?scp=85136978489&partnerID=8YFLogxK
U2 - 10.1039/d2cc02405e
DO - 10.1039/d2cc02405e
M3 - Article
C2 - 35997227
AN - SCOPUS:85136978489
SN - 1359-7345
VL - 58
SP - 10162
EP - 10165
JO - Chemical Communications
JF - Chemical Communications
IS - 73
ER -