Multiancestry, tissue-specific genetics inform type 2 diabetes etiology

Shiu Lun Au Yeung; Gabriel Chun Yin Sung; Ronald Ching Wan Ma

doi:10.1016/j.tig.2026.03.009

Multiancestry, tissue-specific genetics inform type 2 diabetes etiology

Shiu Lun Au Yeung
, Gabriel Chun Yin Sung
, Ronald Ching Wan Ma

Research output: Contribution to journal › Short survey › peer-review

Abstract

Recent work by Bocher et al . used Mendelian randomization to identify hundreds of gene expressions and multiple proteins that likely play a causal role in type 2 diabetes. The study emphasized the importance of ancestry and tissue-specific analyses in elucidating intervention targets.

Original language	English
Pages (from-to)	481-483
Number of pages	3
Journal	Trends in Genetics
Volume	42
Issue number	6
DOIs	https://doi.org/10.1016/j.tig.2026.03.009
Publication status	Published - Jun 2026
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.tig.2026.03.009

Cite this

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title = "Multiancestry, tissue-specific genetics inform type 2 diabetes etiology",

abstract = "Recent work by Bocher et al . used Mendelian randomization to identify hundreds of gene expressions and multiple proteins that likely play a causal role in type 2 diabetes. The study emphasized the importance of ancestry and tissue-specific analyses in elucidating intervention targets.",

author = "\{Au Yeung\}, \{Shiu Lun\} and Sung, \{Gabriel Chun Yin\} and Ma, \{Ronald Ching Wan\}",

note = "Publisher Copyright: {\textcopyright} 2026 Elsevier Ltd.",

year = "2026",

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doi = "10.1016/j.tig.2026.03.009",

language = "English",

volume = "42",

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AU - Au Yeung, Shiu Lun

AU - Sung, Gabriel Chun Yin

AU - Ma, Ronald Ching Wan

PY - 2026/6

Y1 - 2026/6

N2 - Recent work by Bocher et al . used Mendelian randomization to identify hundreds of gene expressions and multiple proteins that likely play a causal role in type 2 diabetes. The study emphasized the importance of ancestry and tissue-specific analyses in elucidating intervention targets.

AB - Recent work by Bocher et al . used Mendelian randomization to identify hundreds of gene expressions and multiple proteins that likely play a causal role in type 2 diabetes. The study emphasized the importance of ancestry and tissue-specific analyses in elucidating intervention targets.

UR - https://www.scopus.com/pages/publications/105035523632

U2 - 10.1016/j.tig.2026.03.009

DO - 10.1016/j.tig.2026.03.009

M3 - Short survey

C2 - 41986223

AN - SCOPUS:105035523632

SN - 0168-9525

VL - 42

SP - 481

EP - 483

JO - Trends in Genetics

JF - Trends in Genetics

IS - 6

ER -

Multiancestry, tissue-specific genetics inform type 2 diabetes etiology

Abstract

UN SDGs

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