Abstract
Cancer is a remarkabe disease characterized with the de-rdgulation of various genetic pathways. The identification of gene markers, some of which carry signatures to clinical relevant physiological effects, sheds light on the development of various clinical applications. A major challenge in marker gene identification is the biological and statistical variability. In particular, we highlight state-of-The-Art methodologies and the latest challenges in marker gene identification from gene microarray data. Moreover, we illustrate the use of a partial least square based approach for identifying gene markers from a Diffuse Large B Cell Lymphoma gene microarray dataset and present new findings.
| Original language | English |
|---|---|
| Title of host publication | Proceedings - 2016 IEEE International Conference on Digital Signal Processing, DSP 2016 |
| Pages | 322-326 |
| Number of pages | 5 |
| ISBN (Electronic) | 9781509041657 |
| DOIs | |
| Publication status | Published - 2 Jul 2016 |
| Externally published | Yes |
| Event | 2016 IEEE International Conference on Digital Signal Processing, DSP 2016 - Beijing, China Duration: 16 Oct 2016 → 18 Oct 2016 |
Publication series
| Name | International Conference on Digital Signal Processing, DSP |
|---|---|
| Volume | 0 |
| ISSN (Electronic) | 2165-3577 |
Conference
| Conference | 2016 IEEE International Conference on Digital Signal Processing, DSP 2016 |
|---|---|
| Country/Territory | China |
| City | Beijing |
| Period | 16/10/16 → 18/10/16 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Diffused Large B cell Lymphoma (DLBCL)
- Marker gene identification
- cancer
- large-scale
- microarray
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