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Marker gene identification for gene expression analysis-Review and new findings for Diffused Large B Cell Lymphoma (DLBCL)

  • Xi Guang Wei
  • , Ho Chun Wu
  • , Shing Chow Chan

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Cancer is a remarkabe disease characterized with the de-rdgulation of various genetic pathways. The identification of gene markers, some of which carry signatures to clinical relevant physiological effects, sheds light on the development of various clinical applications. A major challenge in marker gene identification is the biological and statistical variability. In particular, we highlight state-of-The-Art methodologies and the latest challenges in marker gene identification from gene microarray data. Moreover, we illustrate the use of a partial least square based approach for identifying gene markers from a Diffuse Large B Cell Lymphoma gene microarray dataset and present new findings.

Original languageEnglish
Title of host publicationProceedings - 2016 IEEE International Conference on Digital Signal Processing, DSP 2016
Pages322-326
Number of pages5
ISBN (Electronic)9781509041657
DOIs
Publication statusPublished - 2 Jul 2016
Externally publishedYes
Event2016 IEEE International Conference on Digital Signal Processing, DSP 2016 - Beijing, China
Duration: 16 Oct 2016 → 18 Oct 2016

Publication series

NameInternational Conference on Digital Signal Processing, DSP
Volume0
ISSN (Electronic)2165-3577

Conference

Conference2016 IEEE International Conference on Digital Signal Processing, DSP 2016
Country/TerritoryChina
CityBeijing
Period16/10/16 → 18/10/16

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Diffused Large B cell Lymphoma (DLBCL)
  • Marker gene identification
  • cancer
  • large-scale
  • microarray

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