High-density mapping of de novo focal atrial tachycardias using a new software: Protected low-voltage areas by zones of conduction delay

Konstantinos P. Letsas, Michael Efremidis, George Bazoukis, Stylianos Dragasis, Athanasia Megarisiotou, Panagiotis Mililis, Athanasios Saplaouras, Konstantinos Vlachos, Dimitrios Asvestas, Kosmas Valkanas, Gary Tse, Antonios Sideris

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The pathophysiological mechanism of focal atrial tachycardias (AT) remains obscure. Methods: Fifteen patients (6 males, age 45 ± 18) with focal AT underwent high-density activation mapping using a new software called extended early-meets-late (EEML). Results: Irrespective of the arrhythmia mechanism, low bipolar voltage fractionated signals (0.14 ± 0.10 mV) were seen at the earliest activation site. The mean low-voltage area (LVA) at the earliest activation site was 3.2 ± 1.0 cm2. EEML mapping revealed zones of conduction delay at the borders of LVAs. Conclusions: LVAs protected by zones of slow conduction appears to play an important role in the initiation and maintenance of focal ATs.

Original languageEnglish
Pages (from-to)785-788
Number of pages4
JournalJournal of Arrhythmia
Volume36
Issue number4
DOIs
Publication statusPublished - 1 Aug 2020
Externally publishedYes

Keywords

  • ablation
  • electroanatomical mapping
  • focal atrial tachycardia

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