TY - JOUR
T1 - Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures
T2 - A systematic review with meta-analysis
AU - Weymann, Alexander
AU - Ali-Hasan-Al-Saegh, Sadeq
AU - Popov, Aron Frederik
AU - Sabashnikov, Anton
AU - Mirhosseini, Seyed Jalil
AU - Liu, Tong
AU - Tse, Gary
AU - Lotfaliani, Mohammadreza
AU - Ghanei, Azam
AU - Testa, Luca
AU - D’Ascenzo, Fabrizio
AU - Benedetto, Umberto
AU - Dehghan, Hamidreza
AU - Roever, Leonardo
AU - De Oliveira Sá, Michel Pompeu Barros
AU - Baker, William L.
AU - Yavuz, Senol
AU - Zeriouh, Mohamed
AU - Mashhour, Ahmed
AU - Nombela-Franco, Luis
AU - Jang, Jae Sik
AU - Meng, Lei
AU - Gong, Mengqi
AU - Deshmukh, Abhishek J.
AU - Palmerini, Tullio
AU - Linde, Cecilia
AU - Filipiak, Krzysztof J.
AU - Biondi-Zoccai, Giuseppe
AU - Calkins, Hugh
AU - Stone, Gregg W.
N1 - Publisher Copyright:
Copyright © Polskie Towarzystwo Kardiologiczne 2018.
PY - 2018
Y1 - 2018
N2 - Background: New postoperative atrial fibrillation (POAF) is one of the most critical and common complications after cardiovascular surgery precipitating early and late morbidities. Complete blood count (CBC) is an imperative blood test in clinical practice, routinely used in the examination of cardiovascular diseases. Aim: This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of haematological indices in CBC tests with atrial fibrillation following isolated coronary artery bypass graft (CABG), isolated valvular surgery, or a combination of these treatments. Methods: We conducted a meta-analysis of studies evaluating pre- and postoperative haematological indices in patients with POAF. A comprehensive subgroup analysis was performed to explore potential sources of heterogeneity. Results: A literature search of all major databases retrieved 732 studies. After screening, 22 studies were analysed including a total of 6098 patients. Pooled analysis showed preoperative platelet count (PC) (weighted mean difference [WMD] = –7.07 × 109/L and p < 0.001), preoperative mean platelet volume (MPV) (WMD = 0.53 FL and p < 0.001), preoperative white blood cell count (WBC) (WMD = 0.130 × 109/L and p < 0.001), preoperative neutrophil-to-lymphocyte ratio (NLR) (WMD = 0.33 and p < 0.001), preoperative red blood cell distribution width (RDW) (WMD = 0.36% and p < 0.001), postoperative WBC (WMD = 1.36 × 109/L and p < 0.001), and postoperative NLR (WMD = 0.74 and p < 0.001) as associated factors with POAF. Conclusions: Haematological indices may predict the risk of POAF before surgery. These easily-performed tests should definitely be taken into account in patients undergoing isolated CABG, valvular surgery, or combined procedures.
AB - Background: New postoperative atrial fibrillation (POAF) is one of the most critical and common complications after cardiovascular surgery precipitating early and late morbidities. Complete blood count (CBC) is an imperative blood test in clinical practice, routinely used in the examination of cardiovascular diseases. Aim: This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of haematological indices in CBC tests with atrial fibrillation following isolated coronary artery bypass graft (CABG), isolated valvular surgery, or a combination of these treatments. Methods: We conducted a meta-analysis of studies evaluating pre- and postoperative haematological indices in patients with POAF. A comprehensive subgroup analysis was performed to explore potential sources of heterogeneity. Results: A literature search of all major databases retrieved 732 studies. After screening, 22 studies were analysed including a total of 6098 patients. Pooled analysis showed preoperative platelet count (PC) (weighted mean difference [WMD] = –7.07 × 109/L and p < 0.001), preoperative mean platelet volume (MPV) (WMD = 0.53 FL and p < 0.001), preoperative white blood cell count (WBC) (WMD = 0.130 × 109/L and p < 0.001), preoperative neutrophil-to-lymphocyte ratio (NLR) (WMD = 0.33 and p < 0.001), preoperative red blood cell distribution width (RDW) (WMD = 0.36% and p < 0.001), postoperative WBC (WMD = 1.36 × 109/L and p < 0.001), and postoperative NLR (WMD = 0.74 and p < 0.001) as associated factors with POAF. Conclusions: Haematological indices may predict the risk of POAF before surgery. These easily-performed tests should definitely be taken into account in patients undergoing isolated CABG, valvular surgery, or combined procedures.
KW - Atrial fibrillation
KW - Cardiac surgical procedure
KW - Complete blood count
KW - Coronary artery bypass
KW - Meta-analysis
KW - Review
UR - http://www.scopus.com/inward/record.url?scp=85041179321&partnerID=8YFLogxK
U2 - 10.5603/KP.a2017.0179
DO - 10.5603/KP.a2017.0179
M3 - Article
C2 - 28980298
AN - SCOPUS:85041179321
SN - 0022-9032
VL - 76
SP - 107
EP - 118
JO - Kardiologia Polska
JF - Kardiologia Polska
IS - 1
ER -