Etiopathogenesis of Lyme Carditis

Oscar Hou In Chou; Kyle Hui; Vanessa Hou Cheng Chou; Adrian Baranchuk; Gary Tse

doi:10.1007/978-3-031-41169-4_3

Etiopathogenesis of Lyme Carditis

Oscar Hou In Chou, Kyle Hui, Vanessa Hou Cheng Chou, Adrian Baranchuk, Gary Tse

Health Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

The development of Lyme carditis is largely mediated by the direct invasion of the myocardial tissue and the subsequent triggering of pro-inflammatory changes. Borrelia spp. modulates the expression of proteins, including outer surface adhesins and complement inhibitor proteins, to facilitate pathogenesis; causing the common manifestations of Lyme carditis including atrioventricular block, other arrhythmias, myocarditis, pericarditis, endocarditis and dilated cardiomyopathy via a plethora of mechanisms.

Original language	English
Title of host publication	Lyme Carditis
Subtitle of host publication	From A to Z
Pages	17-27
Number of pages	11
ISBN (Electronic)	9783031411694
DOIs	https://doi.org/10.1007/978-3-031-41169-4_3
Publication status	Published - 1 Jan 2023

Keywords

Autoimmune response
Inflammatory response
Lyme carditis
Myocardial spirochete invasion

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10.1007/978-3-031-41169-4_3

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title = "Etiopathogenesis of Lyme Carditis",

abstract = "The development of Lyme carditis is largely mediated by the direct invasion of the myocardial tissue and the subsequent triggering of pro-inflammatory changes. Borrelia spp. modulates the expression of proteins, including outer surface adhesins and complement inhibitor proteins, to facilitate pathogenesis; causing the common manifestations of Lyme carditis including atrioventricular block, other arrhythmias, myocarditis, pericarditis, endocarditis and dilated cardiomyopathy via a plethora of mechanisms.",

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author = "Chou, {Oscar Hou In} and Kyle Hui and Chou, {Vanessa Hou Cheng} and Adrian Baranchuk and Gary Tse",

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AU - Chou, Oscar Hou In

AU - Hui, Kyle

AU - Chou, Vanessa Hou Cheng

AU - Baranchuk, Adrian

AU - Tse, Gary

N1 - Publisher Copyright: © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.

PY - 2023/1/1

Y1 - 2023/1/1

N2 - The development of Lyme carditis is largely mediated by the direct invasion of the myocardial tissue and the subsequent triggering of pro-inflammatory changes. Borrelia spp. modulates the expression of proteins, including outer surface adhesins and complement inhibitor proteins, to facilitate pathogenesis; causing the common manifestations of Lyme carditis including atrioventricular block, other arrhythmias, myocarditis, pericarditis, endocarditis and dilated cardiomyopathy via a plethora of mechanisms.

AB - The development of Lyme carditis is largely mediated by the direct invasion of the myocardial tissue and the subsequent triggering of pro-inflammatory changes. Borrelia spp. modulates the expression of proteins, including outer surface adhesins and complement inhibitor proteins, to facilitate pathogenesis; causing the common manifestations of Lyme carditis including atrioventricular block, other arrhythmias, myocarditis, pericarditis, endocarditis and dilated cardiomyopathy via a plethora of mechanisms.

KW - Autoimmune response

KW - Inflammatory response

KW - Lyme carditis

KW - Myocardial spirochete invasion

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DO - 10.1007/978-3-031-41169-4_3

M3 - Chapter

AN - SCOPUS:85186098785

SN - 9783031411687

SP - 17

EP - 27

BT - Lyme Carditis

ER -

Etiopathogenesis of Lyme Carditis

Abstract

Keywords

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