TY - JOUR
T1 - Electrocardiograhic characteristics in patients with coronavirus infection
T2 - A single-center observational study
AU - Li, Yi
AU - Liu, Tong
AU - Tse, Gary
AU - Wu, Mingxiang
AU - Jiang, Jingjing
AU - Liu, Ming
AU - Tao, Liang
N1 - Publisher Copyright:
© 2020 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC
PY - 2020/11
Y1 - 2020/11
N2 - Background: A global outbreak of coronavirus disease (COVID-19), caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has emerged since December 2019, in Wuhan, China. However, electrocardiograhic (ECG) manifestations of patients with COVID-19 have not been fully described. We aim to investigate ECG characteristics in COVID-19 patients and risk factors of intensive care unit (ICU) admission. Methods: This retrospective observational study included the patients with COVID-19 at the Wuhan Asia General hospital between February 10, and 26, 2020. Demographic, clinical, and ECG characteristics were collected, and comparisons were made between the ICU and non-ICU admission groups. Logistic regression was used to identify risk factors of ICU admission. Results: Among 135 included patients (median age: 64 years [interquartile range: 48–72]), ST-T abnormalities (40%) were the most common ECG feature, followed by arrhythmias (38%). Cardiovascular disease (CVD) was presented in 48% of the patients. Six (4.4%) died during hospitalization, and 23 (17.0%) were admitted to the ICU. Compared with non-ICU group, the ICU group showed higher heart rate (p =.019) and P-wave duration (p =.039) and was more frequently associated with CVD (p <.001), ST-T abnormalities (p =.007), arrhythmias (p =.003), QTc interval prolongation (p =.003), and pathological Q waves (p <.001). Twenty-seven patients were re-examined ECG during admission, and 17 of them presented new findings compared with their initial ECG presentations. ST-T abnormalities (p =.040) and history of CVD (p =.0047) were associated with increased risk of ICU hospitalization. Conclusions: COVID-19 is frequently related to cardiovascular manifestations including ECG abnormalities and cardiovascular comorbidities. ST-T abnormalities and CVD at admission were associated with increased odds of ICU admission.
AB - Background: A global outbreak of coronavirus disease (COVID-19), caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has emerged since December 2019, in Wuhan, China. However, electrocardiograhic (ECG) manifestations of patients with COVID-19 have not been fully described. We aim to investigate ECG characteristics in COVID-19 patients and risk factors of intensive care unit (ICU) admission. Methods: This retrospective observational study included the patients with COVID-19 at the Wuhan Asia General hospital between February 10, and 26, 2020. Demographic, clinical, and ECG characteristics were collected, and comparisons were made between the ICU and non-ICU admission groups. Logistic regression was used to identify risk factors of ICU admission. Results: Among 135 included patients (median age: 64 years [interquartile range: 48–72]), ST-T abnormalities (40%) were the most common ECG feature, followed by arrhythmias (38%). Cardiovascular disease (CVD) was presented in 48% of the patients. Six (4.4%) died during hospitalization, and 23 (17.0%) were admitted to the ICU. Compared with non-ICU group, the ICU group showed higher heart rate (p =.019) and P-wave duration (p =.039) and was more frequently associated with CVD (p <.001), ST-T abnormalities (p =.007), arrhythmias (p =.003), QTc interval prolongation (p =.003), and pathological Q waves (p <.001). Twenty-seven patients were re-examined ECG during admission, and 17 of them presented new findings compared with their initial ECG presentations. ST-T abnormalities (p =.040) and history of CVD (p =.0047) were associated with increased risk of ICU hospitalization. Conclusions: COVID-19 is frequently related to cardiovascular manifestations including ECG abnormalities and cardiovascular comorbidities. ST-T abnormalities and CVD at admission were associated with increased odds of ICU admission.
KW - arrhythmias
KW - cardiovascular disease
KW - coronavirus disease
KW - electrocardiogram
UR - http://www.scopus.com/inward/record.url?scp=85090996096&partnerID=8YFLogxK
U2 - 10.1111/anec.12805
DO - 10.1111/anec.12805
M3 - Article
C2 - 32951285
AN - SCOPUS:85090996096
SN - 1082-720X
VL - 25
JO - Annals of Noninvasive Electrocardiology
JF - Annals of Noninvasive Electrocardiology
IS - 6
M1 - e12805
ER -