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Dosimetric study of radioadaptive response of zebrafish embryos using PADC-film substrates

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9 Citations (Scopus)

Abstract

We found the alpha-particle priming dose which could effectively induce in vivo radioadaptive response in the embryos of the zebrafish, Danio rerio, to be 4.8-48 μGy, through the apoptotic signals scored in the embryos at 24 h post fertilization. Specially fabricated thin polyallyldiglycol carbonate (PADC) films were used as support substrates for the dechorionated embryos. During irradiation, alpha particles passed through the PADC films to hit the zebrafish embryos, and the alpha-particle tracks were revealed in the films through chemical etching. By determining the number of alpha-particle tracks that coincided with the effective areas of the embryos, the alpha-particle doses were found.

Original languageEnglish
Pages (from-to)1795-1798
Number of pages4
JournalRadiation Measurements
Volume46
Issue number12
DOIs
Publication statusPublished - Dec 2011
Externally publishedYes

Keywords

  • Adaptive response
  • Alpha particles
  • CR-39
  • PADC
  • Zebrafish embryos

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