Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

L. Xu; J. Chen; Y. Zhang; C. C.C. Cheung; P. K.S. Lam

doi:10.2166/wst.2001.0085

Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

L. Xu
, J. Chen
, Y. Zhang
, C. C.C. Cheung
, P. K.S. Lam

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.

Original language	English
Pages (from-to)	155-160
Number of pages	6
Journal	Water Science and Technology
Volume	43
Issue number	2
DOIs	https://doi.org/10.2166/wst.2001.0085
Publication status	Published - 2001
Externally published	Yes

Keywords

ATPase
Benzo[a]pyrene
EROD
GST, DNA adduct
Gold-lined sea bream

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10.2166/wst.2001.0085

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title = "Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene",

abstract = "Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.",

keywords = "ATPase, Benzo[a]pyrene, EROD, GST, DNA adduct, Gold-lined sea bream",

author = "L. Xu and J. Chen and Y. Zhang and Cheung, \{C. C.C.\} and Lam, \{P. K.S.\}",

year = "2001",

doi = "10.2166/wst.2001.0085",

language = "English",

volume = "43",

pages = "155--160",

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}

TY - JOUR

T1 - Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

AU - Xu, L.

AU - Chen, J.

AU - Zhang, Y.

AU - Cheung, C. C.C.

AU - Lam, P. K.S.

PY - 2001

Y1 - 2001

N2 - Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.

AB - Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.

KW - ATPase

KW - Benzo[a]pyrene

KW - EROD

KW - GST, DNA adduct

KW - Gold-lined sea bream

UR - https://www.scopus.com/pages/publications/0035106458

U2 - 10.2166/wst.2001.0085

DO - 10.2166/wst.2001.0085

M3 - Article

C2 - 11380174

AN - SCOPUS:0035106458

SN - 0273-1223

VL - 43

SP - 155

EP - 160

JO - Water Science and Technology

JF - Water Science and Technology

IS - 2

ER -

Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

Abstract

Keywords

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