TY - JOUR
T1 - Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene
AU - Xu, L.
AU - Chen, J.
AU - Zhang, Y.
AU - Cheung, C. C.C.
AU - Lam, P. K.S.
PY - 2001
Y1 - 2001
N2 - Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.
AB - Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.
KW - ATPase
KW - Benzo[a]pyrene
KW - EROD
KW - GST, DNA adduct
KW - Gold-lined sea bream
UR - http://www.scopus.com/inward/record.url?scp=0035106458&partnerID=8YFLogxK
U2 - 10.2166/wst.2001.0085
DO - 10.2166/wst.2001.0085
M3 - Article
C2 - 11380174
AN - SCOPUS:0035106458
SN - 0273-1223
VL - 43
SP - 155
EP - 160
JO - Water Science and Technology
JF - Water Science and Technology
IS - 2
ER -