Ageing and the Autonomic Nervous System

Michael Takla, Khalil Saadeh, Gary Tse, Christopher L.H. Huang, Kamalan Jeevaratnam

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Citations (Scopus)

Abstract

The vertebrate nervous system is divided into central (CNS) and peripheral (PNS) components. In turn, the PNS is divided into the autonomic (ANS) and enteric (ENS) nervous systems. Ageing implicates time-related changes to anatomy and physiology in reducing organismal fitness. In the case of the CNS, there exists substantial experimental evidence of the effects of age on individual neuronal and glial function. Although many such changes have yet to be experimentally observed in the PNS, there is considerable evidence of the role of ageing in the decline of ANS function over time. As such, this chapter will argue that the ANS constitutes a paradigm for the physiological consequences of ageing, as well as for their clinical implications.

Original languageEnglish
Title of host publicationSubcellular Biochemistry
PublisherSpringer Science and Business Media B.V.
Pages201-252
Number of pages52
DOIs
Publication statusPublished - 2023
Externally publishedYes

Publication series

NameSubcellular Biochemistry
Volume103
ISSN (Print)0306-0225

Keywords

  • Ageing
  • Autonomic
  • Clinical
  • Glial
  • Neuronal

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