A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

On Ying Yuen; Shun Man Wong; Kin Fai Chan; Chau Ming So; Fuk Yee Kwong

doi:10.1055/s-0033-1338660

A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

On Ying Yuen
, Shun Man Wong
, Kin Fai Chan
, Chau Ming So
, Fuk Yee Kwong

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).

Original language	English
Article number	ss-2014-h0287-op
Pages (from-to)	2826-2832
Number of pages	7
Journal	Synthesis (Germany)
Volume	46
Issue number	20
DOIs	https://doi.org/10.1055/s-0033-1338660
Publication status	Published - 16 Oct 2014
Externally published	Yes

Keywords

Suzuki-Miyaura reaction
aryl chloride
arylation
palladium
potassium aryltrifluoroborates
water

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10.1055/s-0033-1338660

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title = "A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex",

abstract = "General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol\% Pd).",

keywords = "Suzuki-Miyaura reaction, aryl chloride, arylation, palladium, potassium aryltrifluoroborates, water",

author = "Yuen, \{On Ying\} and Wong, \{Shun Man\} and Chan, \{Kin Fai\} and So, \{Chau Ming\} and Kwong, \{Fuk Yee\}",

note = "Publisher Copyright: {\textcopyright} Georg Thieme Verlag Stuttgart New York.",

year = "2014",

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doi = "10.1055/s-0033-1338660",

language = "English",

volume = "46",

pages = "2826--2832",

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T1 - A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

AU - Yuen, On Ying

AU - Wong, Shun Man

AU - Chan, Kin Fai

AU - So, Chau Ming

AU - Kwong, Fuk Yee

N1 - Publisher Copyright: © Georg Thieme Verlag Stuttgart New York.

PY - 2014/10/16

Y1 - 2014/10/16

N2 - General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).

AB - General examples of the palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl or heteroaryl chlorides with potassium aryl- or heteroaryltrifluoroborates in water are presented. The palladium complex comprising of palladium(II) acetate and 'CPCy Phendole-phos' is found to be a highly effective catalyst system for this coupling reaction with low catalyst loading (down to 0.005 mol% Pd).

KW - Suzuki-Miyaura reaction

KW - aryl chloride

KW - arylation

KW - palladium

KW - potassium aryltrifluoroborates

KW - water

UR - https://www.scopus.com/pages/publications/84928708073

U2 - 10.1055/s-0033-1338660

DO - 10.1055/s-0033-1338660

M3 - Article

AN - SCOPUS:84928708073

SN - 0039-7881

VL - 46

SP - 2826

EP - 2832

JO - Synthesis (Germany)

JF - Synthesis (Germany)

IS - 20

M1 - ss-2014-h0287-op

ER -

A General Suzuki-Miyaura Coupling of Aryl Chlorides with Potassium Aryltrifluoroborates in Water Catalyzed by an Efficient CPCy Phendole-phos-Palladium Complex

Abstract

Keywords

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